INTRODUCTION OF TABLETS
tablet-introduction,tablet |
Tablet
is defined as a
compressed solid dosage form containing
medicaments with or without excipients.
According to the Indian
pharmacopoeia-pharmaceutical tablets are solid, flat or biconvex dishes, unit
dosage form, prepared by compressing a drug or a mixture of drugs, with or
without diluents.
tablet-introduction |
ADVANTAGES OF TABLET AS DOSAGE FORM-:
·
More stable than liquid dosage forms,
may have longer shelf –life.
·
Portable, easy to handle.
·
Better in accuracy & precision of
dose.
·
Cost is lowest of all oral dosage
form.
·
Easiest and cheapest to package and
strip.
·
Objectionable odorand bitter taste can
be masked by coating technique.
·
Greatest chemical and microbial
stability over all oral dosage form.
·
Sustained release product is possible
by enteric coating.
DISADVANTAGES OF TABLETS AS A DOSAGE FORM-:
·
Difficult to swallow in case of
children and unconscious patients.
·
Disintegration &
dissolution of tablets
are rate determining
factors for drug absorption &
usually they show slow onset of action.
·
Slower onset of action than parental
dosage form.
·
Drugs having low bulk density cannot
be formulated into dense compact tablets.
·
Tablets cannot be used in emergency
cases.
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