1. INTRODUCTION TO CAPSULES-
Capsules are solid dosage forms in which drug substance is enclosed within
hard or soft soluble shell. The shells are generally formed from gelatin.
Capsules are of two types:
1. Hard gelatin capsules
2. Soft gelatin capsules
A. ADVANTAGES OF CAPSULES:
· Capsules are tasteless, odorless and can easily be administered.
· Combination of powders can be incorporated
· They are attractive in appearance.
· The drugs having un-pleasant odor and taste are enclosed in a tasteless shell.
· They can be filled quickly and conveniently.
· Physician can change the dose and combination of drug according to patient requirement.
· They are economical.
· They are easy to handle and carry.
B. DISADVANTAGES OF CAPSULES:
· Hygroscopic drugs are not suitable for filling into capsules, because they absorb water present in capsule shell makes shell very brittle and ultimately lead to crumble into pieces.
· The concentrated solutions which require previous dilution are unsuitable for capsules because if administered as such lead to irritation in the stomach
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